Episode 6: The biology of it all

Bruce Marshall describes the journey of developing biologic knowledge of Cystic Fibrosis (CF), an inherited condition. He illustrates the variety of methods that contributed to this development and suggests how CF knowledge impacts the design of coproduced services and the lives of those with Cystic Fibrosis

Transcript

Guests

bruce

Bruce Marshall

M.D., MMM, Chief Medical Officer and Executive Vice President, Cystic Fibrosis (CF) Foundation.

More about Bruce

Bruce Marshall’s senior role at CF Foundation includes leadership of the care center network, overseeing quality improvement, clinical practice guidelines, the patient registry and educational resources.

From 1988 to 2002, Bruce was Director of a leading Adult CF program at Utah University School of Medicine. His research interests have centered on CF epidemiologic and clinical studies, including use of survival models for assessing the impact of lung transplantation, and chronic azithromycin in CF treatment. Before joining the CF Foundation, Bruce was an Associate Professor at the Utah School of Medicine.

Bruce earned his BA at Johns Hopkins University and his MD at the University of Maryland School of Medicine. He trained in internal medicine at Strong Memorial Hospital, University of Rochester, and as part of a pulmonary fellowship at the Boston University School of Medicine. He also holds a Master’s Degree in Medical Management from Carnegie Mellon University. Bruce is board certified in Internal Medicine and Pulmonary Disease.

Bruce speaks with Paul about the development of biologic knowledge in CF.

Supplementary materials

Readings

Trivedi BP. Breath From Salt: A Deadly Genetic Disease, a New Era in Science, and the Patients and Families Who Changed Medicine Forever. 2020 BenBella Books: Dallas, Texas

Karol Fiedorczuk and Jue Chen. “Mechanism of CFTR correction by type I folding correctors.” Cell. Published online January 6, 2022. doi: 10.1016/j.cell.2021.12.009

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